Abstract Background Magnolia champaca, commonly known as champak is a well-known tree due to its highly fragrant flowers.Champak floral scent is attributed to a complex mix of volatile organic compounds (VOCs).These aromatic flowers are widely used in flavors and fragrances industry.Despite its commercial importance, the VOC biosynthesis pathways i
RD Brooks,1 PE Jolly,1 L Marsh,1 JM Velazquez,1 L Padilla,1 WG Jaoko21Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA; 2Department of Medical Microbiology, School of Medicine, University of Nairobi, Nairobi, KenyaCorrespondence: PE JollyDepartment of Epidemiology, University of Alabama at
Inhibiting Hsp90 chaperone roles using 17AAG induces cytostasis or apoptosis in tumor cells through destabilization of several mutated cancer neflintw-r6mpw promoting proteins.Although mitochondria are central in deciding the fate of cells, 17AAG induced effects on tumor cell mitochondria were largely unknown.Here, we show that Hsp90 inhibition wit
The conventional narrative states that the steadily rising incidence of melanoma among fair-skinned Caucasian populations during the last decades is caused by excessive UV-exposure.There is, however, no doubt that other factors had a significant impact on the rising incidence of melanoma.Pre-1980s the clinical diagnosis of melanoma was based on gro